False discovery rates: a new deal
نویسندگان
چکیده
منابع مشابه
False discovery rates: a new deal
We introduce a new Empirical Bayes approach for large-scale hypothesis testing, including estimating false discovery rates (FDRs), and effect sizes. This approach has two key differences from existing approaches to FDR analysis. First, it assumes that the distribution of the actual (unobserved) effects is unimodal, with a mode at 0. This "unimodal assumption" (UA), although natural in many cont...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2016
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxw041